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New paper: mpox vaccination and behavioural change in the DRC

An age-structured model of mpox in the Democratic Republic of Congo compares vaccination with behavioural change among high-risk groups.

Dr. Andrew Omame, Dr. Chigozie Louisa J. Ugwu and Prof. Woldegebriel Assefa Woldegerima, with collaborators, have published a new paper in One Health (Volume 22).

“Assessing the impact of vaccination and behavioural change on Mpox transmission in high-risk groups in the Democratic Republic of Congo using an age-structured mathematical model” looks at how vaccination and behaviour-driven contact reduction among high-risk adults work together, within an age- and risk-structured modelling framework.

Key findings

  • Among adults, behavioural change does more than vaccination to reduce mpox transmission.
  • Vaccinating children has a larger effect than either reducing contacts or immunizing adults.
  • Starting a 50% reduction in contacts among high-risk adults about 20 weeks earlier gives a further 20% fall in cumulative cases.

The study provides evidence for allocating vaccine and prioritizing behavioural interventions among high-risk groups, with the aim of preventing sustained transmission in the DRC.

Congratulations to the whole team on this publication.

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